A safe and efficient synthesis of 4,7-dibromo[1,2,5]thiadiazolo[3,4-d]pyridazine from the commercial diaminomaleonitrile is reported.Conditions for selective aromatic nucleophilic substitution of one or two bromine atoms by canon imageclass mf227dw oxygen and nitrogen nucleophiles are found, whereas thiols formed the bis-derivatives only.Buchwald-H

A reliable tuber yield prognosis requires a complex statistical analysis of potato nutritional status in the fully developed 4th leaf at the onset of tuberisation.This hypothesis was validated in the neflintw-r6mpw series of field experiments conducted in 2006-2008 in Poland.The experimental design was composed of two nitrogen (N) rates (60, 120 kg

Neuroblastoma (NB) is the most common extracranial napoleon concealer solid tumor in childhood, with grim prognosis in a half of patients.Exosomes are nanometer-sized membrane vesicles derived from the multivesicular bodies (MVBs) of the endocytic pathway and released by normal and neoplastic cells.Tumor-derived exosomes have been shown in differen

Abstract Introduction and objective Modern and intelligent triage systems are used today due to the growing trend of disasters and emergencies worldwide and the increase in the number of injured people facing the challenge of using traditional triage methods.The main objective of this read more study is to investigate the application of artificial